Evidence Based Clinical Application of Personalised Medicine
Gain insight into how you can reduce the risk of new treatments having insufficient documented effects, when personalised medicine becomes an integrated part of the clinical settings throughout the health care system.
The implementation of personalised medicine represents the potential for a paradigm shift in disease prevention and treatment, based on optimizing individualized intervention.
During the course, you will gain a theoretical understanding of how relevant scientific evidence is obtained, in order to document the clinically beneficial applicability of interventions aimed at optimizing the treatment of the individual patient based on their unique features and characteristics. In addition, you will gain knowledge on how to ensure that that the usefulness of this evidence is maintained over time, after its clinical application is introduced into everyday clinical settings across the health care system.
You will be introduced to the varying degrees of evidence-building, and how the scientific findings can be internally and externally validated.
Innovative approaches to obtaining evidence are discussed, with a special focus on the unique challenges that a personal medicine approach has, as opposed to traditional evidence-building, by the study of groups of patients.
Approaches to quantifying the beneficial effect of these interventions, and any unintended consequences, are elucidated.
You will gain insight into the required investments and the existing legal challenges pertaining to the implementation and maintenance of such interventions in the operational part of the healthcare system.
- Why do not all patients with a disease have the same effect of a medicine?
- Evidence creation for new medicine
- Strategic questions rather than A vs. B
- Draw on electronic knowledge in the specific clinical situation
- Cost-effective treatment
Lectures and group/project work
Expect significant preparation time for all parts of the course
The course concludes with a written assignment and an oral defense. The written assignment and oral defense can be done individually or in groups. The project work will run in parallel with the teaching.
Jens Lundgren
Professor of Infectious Diseases, Chief Physician, Dr.med., Department of Clinical Medicine, University of Copenhagen.
Centre leader, Centre of Excellence for Personalised Medicine of Infectious Complications in Immune Deficiency (PERSIMUNE), Danish National Research Foundation, Rigshospitalet.
After the course you will:
- Be able to describe approaches to the development of evidence for medical interventions in patient care.
- Be able to discuss the unique challenges in obtaining this evidence in connection with personalised medicine, rather than the traditional evidence approach of groups of patients, as well as explain innovative approaches to dealing with these challenges.
- Be able to explain, in connection with the implementation of new interventions based on automated computer science, how to separate interventions where evidence of usefulness already exists (and where the automation therefore aims to optimize workflows) from interventions where the evidence base is not sufficiently substantiated.
- Be able to describe approaches and pitfalls in the introduction and maintenance of the clinical quality of new interventions based on automated computer-generated information. Both in terms of clinical value as well as legal division of responsibilities.
- Be able to account for the quantification of the clinically beneficial conditions of new interventions in relation to the necessary public investments.
- Be able to analyze and critically approach the construction of clinical evidence by using personalised medicine in the health care system.
- Be able to communicate knowledge about these relationships to patients, colleagues and other professional groups
- Be able to identify the opportunities and challenges in one's own department / own subject area that are important for the development of personalised medicine
- Be able to plan research, development, validation and implementation of clinical evidence for interventions based on personalised medicine.
- Be able to seek out and apply the latest scientific literature on these matters.
Continuing professional development for medical doctors, academics within the health care system, research environments, medicinal industries and organisations working with personalised medicine.
You must meet the following criteria to be admitted to this course:
- Hold a relevant master degree or equivalent
- Have a minimum 2 years of professional experience within personal medicine in a clinical, research or academic field
- Be proficient in English
Find detailed information about the current admission criteria (in Danish).
This course is offered as an elective course on the Master of personalised medicine, which is a Danish master’s programme (Master i personlig medicin).
Priority is given to students enrolled on Master of personalised medicin. Once the enrolled students have been admitted to the course, the remaining seats are distributed on a first-come, first-served basis.
Course capacity: 30 seats.
| Duration | 6 days on campus (3x2 days) |
|
Dates |
2-3 September 2024 - Campus |
| Frequency: | Available once per year |
| Place | University of Copenhagen, Denmark |
| Price | EU/EAA Citizens: 15.000 DKK Non EU/EAA Citizens: 20.600 DKK Terms of Payment (in Danish) |
| Level and Credit | Master course; 7,5 ECTS |
| Examination | See exam plan |
| Application deadline |
8 July 2024 |
| Admission: | To be admitted you must meet the admission criteria for Master i Personlig Medicin (in Danish) |
*The form is in Danish, please contact the admission office if needed, master@sund.ku.dk.
The opening of the application period is announced via the programme newsletter (in Danish)